N-Nitroso Clozapine Impurity 23 CAS CATO-C4X-134023

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-134023
Molecular FormulaC13H10ClN3O3
Molecular Weight291.69 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

N-Nitroso Clozapine Impurity 23 CAS CATO-C4X-134023 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 291.69 g/mol gives N-Nitroso Clozapine Impurity 23 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

N-Nitroso Clozapine Impurity 23 (CAS CATO-C4X-134023) is a certified pharmaceutical impurity reference standard with the molecular formula C13H10ClN3O3 and a molecular weight of 291.69 g/mol.

N-Nitroso Clozapine Impurity 23 (C13H10ClN3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H10ClN3O3
Molecular Weight291.69 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity≥95%
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Nitrogen Atoms3

Related N Standards

Recommended Standards

Why CATO?