Baclofen Impurity 36 CAS CATO-C4X-101236
| CAS No. | CATO-C4X-101236 |
| Molecular Formula | C15H13ClO5 |
| Molecular Weight | 308.71 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Baclofen Impurity 36 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Baclofen Impurity 36 (CAS CATO-C4X-101236, C15H13ClO5) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution, Baclofen Impurity 36 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 308.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Baclofen Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H13ClO5 |
| Molecular Weight | 308.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Baclofen Standards
- Baclofen Impurity 48 (CAS CATO-C4X-101248)
- Baclofen Impurity 49 (CAS CATO-C4X-101249)
- Baclofen Impurity 50 (CAS CATO-C4X-101250)
- Baclofen Impurity 58 (CAS CATO-C4X-101258)
- Baclofen impurity 43 (CAS CATO-C4X-101243)
- Baclofen impurity 44 (CAS CATO-C4X-101244)
- Baclofen Impurity 65 (CAS CATO-C4X-101265)
- Baclofen impurity 9 (CAS 101104-10-3)
Recommended Standards
- Tert-butyl ((5-chloro-4-(difluoromethoxy)pyridin-2-yl)methyl)carbamate (CAS 2231675-32-2)
- 2-(4-Chlorophenyl)hexahydro-1H-pyrrolo[3',4':4,5]isoxazolo[3,2-c][1,4]oxazine-1,3(2H)-dione (CAS 1212336-08-7)
- Tert-butyl ((3-chloro-4-(difluoromethoxy)pyridin-2-yl)methyl)carbamate (CAS 2231676-55-2)
- Methyl 2-chloro-4-morpholinopyrido[2,3-d]pyrimidine-7-carboxylate (CAS 1227958-54-4)
- Betamethasone Impurity 130 (CAS CATO-C4X-1437130)
- Norepinephrine Impurity 127 (CAS 94593-04-1)
- Carbidopa impurity 39 (CAS 2354546-08-8)
- 4-(Dibutylamino)-2-methoxybenzaldehyde (CAS 103893-16-9)
- 2-Amino-2-(3-isopropyl-1-methyl-1h-1,2,4-triazol-5-yl)ethan-1-ol (CAS 1341083-46-2)
- 1-(5-Bromo-1h-indol-2-yl)ethan-1-amine (CAS 1270476-46-4)
- Hexachlorobenzene (CAS 118-74-1)
- N-(5-nitropyridin-2-yl)cyclopropanecarboxamide (CAS 26207-88-5)
- 6-(Quinolin-3-yl)hex-5-yn-1-ol (CAS 88940-61-8)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
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