Clindamycin Phosphate EP Impurity H CAS CATO-C4X-134135

Purity >90%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-134135
Molecular FormulaC18H35ClN2O11P2S
Molecular Weight584.94 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Clindamycin Phosphate EP Impurity H CAS CATO-C4X-134135 chemical structure

Description

The occurrence of Clindamycin Phosphate EP Impurity H is closely related to an amide group, a sulfone group, a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Clindamycin Phosphate EP Impurity H (CAS CATO-C4X-134135), a pharmacopoeial impurity reference standard (molecular formula C18H35ClN2O11P2S, MW 584.94 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C18H35ClN2O11P2S, Clindamycin Phosphate EP Impurity H contains an amide group, a sulfone group, a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic functional-group stretching vibrations in infrared spectroscopy. The molecular weight of 584.94 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H35ClN2O11P2S
Molecular Weight584.94 g/mol
Purity>90%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)2.0
Halogen ContentCl-containing
Nitrogen Atoms2
Sulfur Atoms1

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