Clindamycin Phosphate EP Impurity I CAS 1309048-48-3
| CAS No. | 1309048-48-3 |
| Molecular Formula | C18H35ClN2O11P2S |
| Molecular Weight | 584.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Clindamycin Phosphate EP Impurity I (CAS 1309048-48-3, C18H35ClN2O11P2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amide group, a sulfone group, a phosphate ester group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, Clindamycin Phosphate EP Impurity I is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 584.94 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C18H35ClN2O11P2S |
| Molecular Weight | 584.94 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Clindamycin Standards
- Clindamycin Impurity 132 (CAS CATO-C4X-1341132)
- Clindamycin Pyrophosphate (CAS CATO-C4X-1341147)
- Clindamycin Phosphate EP Impurity H (CAS CATO-C4X-134135)
- Clindamycin Palmitate Impurity 71 (CAS CATO-C4X-134171)
- Clindamycin Phosphas Impurity 42 (CAS CATO-C4X-134142)
- Clindamycin Laurate (CAS 763863-68-9)
- Clindamycin Impurity 168 (CAS CATO-C4X-1341168)
- Clindamycin Impurity 15 (CAS CATO-C4X-134115)
Recommended Standards
- Tri-o-tolylsilyl stearate (CAS 18857-55-1)
- (1,1,5,5-Tetramethyl-3,3-diphenyltrisiloxane-1,5-diyl)bis(propane-3,1-diyl) bis(2-methylacrylate) (CAS 1581235-15-5)
- 2-[2-[2-(Tetradecyloxy)ethoxy]ethoxy]ethyl palmitate (CAS 84605-14-1)
- Trihexyphenidyl Impurity 21 (CAS CATO-C4X-185721)
- Itraconazole Impurity 82 (CAS CATO-C4X-149782)
- Sitafloxacin impurity 77 (CAS 2412444-06-3)
- Natamycin Impurity 14 (CAS CATO-C4X-204014)
- 3-(4-chlorophenyl)cyclohexan-1-one (CAS 136333-71-6)
- 4,4-Dimethyltetrahydro-2H-pyran-2-one (CAS 22791-80-6)
- Oxetane-3-boronic Acid Pinacol Ester (CAS 1396215-84-1)
- 4-(P-tolyl)tetrahydro-2H-pyran-4-ol (CAS 853886-97-2)
- 8-amino-3,7-dihydro-1H-purine-2,6-dione (CAS 5461-03-0)
- Q7AO2R1M0B 2235-54-3 Ammonium lauryl sulfate Dodecyl ammonium sulfate Sulfuric acid, monododecyl ester, ammonium salt Ammonium dodecyl sulphate Sulfuric acid, monododecyl ester, ammonium salt (1:1) Akyposal als 33 Ammonium dodecyl sulfate Ammonium n-dodecyl sulfate Caswell No. 044B Conco sulfate A EINECS 218-793-9 EPA Pesticide Chemical Code 079028 HSDB 2101 Lauryl ammonium sulfate Lauryl sulfate ammonium salt Maprofix NH Montopol LA 20 Neopon LAM Presulin Richonol AM Sinopon Sipon LA 30 Siprol L22 Siprol 422 Sterling AM Sulfuric acid, lauryl ester, ammonium salt Texa pon A 400 Texapon A 400 Texapon special UNII-Q7AO2R1M0B Dodecyl sulfate ammonium salt (CAS 2235-54-3)
- Semaglutide Impurity 144 (CAS 394210-59-4)
Why CATO?
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