Clindamycin Impurity 47 CAS CATO-C4X-134147
| CAS No. | CATO-C4X-134147 |
| Molecular Formula | C18H33ClN2O6S |
| Molecular Weight | 440.98 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Clindamycin Impurity 47 (C18H33ClN2O6S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Clindamycin Impurity 47 (CAS CATO-C4X-134147, C18H33ClN2O6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H33ClN2O6S |
| Molecular Weight | 440.98 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Clindamycin Standards
- Clindamycin Sulfoxide (S-Isomer) (CAS 887607-49-0)
- Clindamycin Impurity 151 (CAS CATO-C4X-1341151)
- Clindamycin Sulfoxide (R-Isomer) (CAS 887607-53-6)
- Clindamycin Phosphas Impurity 44 (CAS 22431-46-5)
- Clindamycin Impurity 117 (CAS CATO-C4X-1341117)
- Clindamycin Impurity 134 (CAS CATO-C4X-1341134)
- Clindamycin Impurity 59 (CAS CATO-C4X-134159)
- Clindamycin Impurity 72 (CAS CATO-C4X-134172)
Recommended Standards
- 3-((4-Chloro-N-methylphenyl)sulfonamido)-N-(2-(thiophen-2-yl)ethyl)thiophene-2-carboxamide (CAS 1251681-50-1)
- 1-((4-chlorophenyl)(phenyl)methyl)-4-tosylpiperazine (CAS 163837-56-7)
- 2-((4-Allyl-5-(4-(tert-butyl)phenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-chlorophenyl)acetamide (CAS 538337-08-5)
- Levocetirizine Impurity 9 (CAS 942283-97-8)
- Ciclesonide Impurity 11 (CAS CATO-C4X-320111)
- Relugolix Impurity 205 (CAS CATO-C4X-2429205)
- Resmetirom Impurity 23 (CAS 2768217-12-3)
- 3-Phenyl-5-[(2,4,5-trichlorophenoxy)methyl]-1,2-oxazole (CAS 478066-43-2)
- 6-Chloro-2-(ethoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 871730-27-7)
- Landiolol Impurity 24 (CAS CATO-C4X-262124)
- 3-[3-(3,4-Dichlorophenyl)-3-piperidinyl]-1-propanol (CAS 182621-51-8)
- Methyl (Dimethoxyphosphinothioylthio)acetate (CAS 757-86-8)
- Vinclozolin (CAS 50471-44-8)
- Tirzepatide-d7 Ditrifluoroacetate (CAS CATO-CPTD788698)
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