Voriconazole Impurity 63 CAS CATO-C4X-136663
| CAS No. | CATO-C4X-136663 |
| Molecular Formula | 2*C14H11Cl2F3N2O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Voriconazole Impurity 63 (C14H11Cl2F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Voriconazole Impurity 63 (CAS CATO-C4X-136663), a pharmacopoeial impurity reference standard (molecular formula C14H11Cl2F3N2O, MW 351.15 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | 2*C14H11Cl2F3N2O |
| Molecular Weight | 351.15 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Voriconazole Standards
- Voriconazole Impurity 70 (CAS 115617-41-9)
- Voriconazole Impurity 31 (CAS 1157981-64-0)
- Voriconazole Impurity 60 (CAS 116622-90-3)
- Voriconazole Impurity 59 (CAS 1185186-22-4)
- Voriconazole-d3 (CAS 1217661-14-7)
- Voriconazole-d3 N-OxideDISCONTINUED. Please see V760013 (CAS 1217851-84-7)
- Voriconazole Impurity 44 (CAS 1289559-66-5)
- Voriconazole Impurity 65 (CAS 1289559-76-7)
Recommended Standards
- Febuxostat Impurity 6 (CAS 1239233-87-4)
- Voriconazole EP Impurity C (CAS 137234-88-9)
- Ilaprazole Impurity 171 (CAS CATO-C4X-1130171)
- 6-Fluoro-1,2,3,4-tetrahydronaphthalen-2-ol (CAS 85072-31-7)
- 2-Iodo-4-nitrotoluene, 97% (CAS 7745-92-8)
- 2-([2,2'-Bithiophen]-3-yl)acetic acid (CAS 114973-62-5)
- 3',6-Difluoro-[1,1'-biphenyl]-2-sulfonyl chloride (CAS 1214332-20-3)
- 2,3,4,5-Tetrachlorophenol acetate (CAS 4901-57-9)
- 1-(3,4-Dichlorophenyl)-2-(methylsulfonyl)ethan-1-one (CAS 344275-49-6)
- Liraglutide(5-31)TFA Salt (CAS CATO-C4X-19924)
Why CATO?
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