Voriconazole Impurity 31 CAS 1157981-64-0
| CAS No. | 1157981-64-0 |
| Molecular Formula | C10H7F2N3O |
| Molecular Weight | 223.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Voriconazole Impurity 31 (CAS 1157981-64-0), a pharmacopoeial impurity reference standard (molecular formula C10H7F2N3O, MW 223.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Voriconazole Impurity 31 (C10H7F2N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C10H7F2N3O |
| Molecular Weight | 223.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Voriconazole Standards
- Voriconazole Impurity N2 (CAS 168479-96-7)
- Voriconazole Impurity 33 (CAS 1449785-88-9)
- Voriconazole Impurity 78 (CAS 351042-08-5)
- Voriconazole Impurity 79 (CAS CATO-C4X-136679)
- Voriconazole EP Impurity E(Voriconazole Related Compound F) (CAS 5872-08-2)
- Voriconazole EP Impurity E (1R)-Isomer (CAS 35963-20-3)
- Voriconazole Impurity 86 (CAS CATO-C4X-136686)
- Voriconazole Impurity 72 (CAS CATO-C4X-136672)
Recommended Standards
- Ticagrelor Impurity 121 (CAS 378236-67-0)
- Fluconazole Impurity 46 (CAS 2013304-99-7)
- Fluconazole Impurity 41 (CAS CATO-C4X-101941)
- Calcitonin Impurity 20 (CAS CATO-C4X-221820)
- Sacubitril impurity 42 (CAS CATO-C4X-280942)
- Propofol Impurity 27 (CAS 20170-32-5)
- Relebactam Impurity 53 (CAS CATO-C4X-214453)
- 2,6-Dibromo-4-iodophenol (CAS 187407-15-4)
- 3-methoxyazetidine-3-carbonitrile;hydrochloride (CAS 2227206-17-7)
- 2-Isopropyl-5-methylcyclohexyl 2-(2-chloroacetamido)benzoate (CAS 1005135-85-2)
- 2,6-Dibromo-3-nitropyridin-4-amine (CAS 848470-14-4)
- 2-Nitro-5-(prop-2-yn-1-ylamino)benzoic acid (CAS 1019386-49-2)
- 5-Fluoro-2-(4-methyl-1h-pyrazol-1-yl)benzaldehyde (CAS 1179794-27-4)
- Semaglutide Main Chain P29 (CAS 1169630-82-3)
Why CATO?
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