Metoprolol Impurity 49 CAS CATO-C4X-136749
| CAS No. | CATO-C4X-136749 |
| Molecular Formula | - |
| Molecular Weight | 303.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Metoprolol Impurity 49 is closely related to deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Metoprolol Impurity 49 (CAS CATO-C4X-136749, C15H17D7N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Metoprolol Impurity 49 (C15H17D7N2O4) contains deuterium isotope labeling, a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Metoprolol Impurity 49 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H17D7N2O4 |
| Molecular Weight | 303.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Metoprolol Standards
- Metoprolol Impurity 48 (CAS CATO-C4X-136748)
- Metoprolol Acid-d5 Ethyl Ester (CAS 1189704-28-6)
- Metoprolol Acid Ethyl Ester (CAS 29112-40-1)
- Metoprolol Impurity 52 (CAS CATO-C4X-136752)
- Metoprolol Impurity 30 (CAS 56392-16-6)
- Metoprolol Impurity 43 (CAS CATO-C4X-136743)
- Metoprolol Impurity 28 (CAS 73723-85-0)
- rac Metoprolol-d7 (CAS 959787-96-3)
Recommended Standards
- N,N-Dicyclohexyl-4-fluorobenzamide (CAS 330684-17-8)
- Nicergoline Impurity 11 (CAS CATO-C4X-208511)
- N,N-Dicyclohexyl-2-fluorobenzamide (CAS 574715-85-8)
- 6PPD-quinone-D5 (CAS 2750119-14-1)
- Bacitracin Impurity H (CAS 144572-55-4)
- Apalutamide Impurity 70 (CAS 1427081-81-9)
- Hydroxychloroquine EP Impurity G (CAS 86-98-6)
- 1-(2-aminopropoxy)-4-tert-butylbenzene (CAS 42909-91-1)
- N-Methyl-4-(1-piperazinyl)benzenesulfonamide (CAS 929342-36-9)
- Rel-((1S,6S)-6-aminocyclohex-3-en-1-yl)methanol (CAS 98769-57-4)
- 3-amino-1-methylpiperidin-2-one hydrochloride (CAS 1422130-18-4)
- Crizotinib impurity 12 (CAS CATO-C4X-102512)
- 4-Methyl-3-(N-(pyridin-2-yl)sulfamoyl)-N-(p-tolyl)benzamide (CAS 5211-15-4)
- Glucagon receptor antagonist I (CAS 438618-32-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com