Mianserin Impurity 66 CAS CATO-C4X-136966
| CAS No. | CATO-C4X-136966 |
| Molecular Formula | C9H12ClN |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 206.11 g/mol gives Mianserin Impurity 66 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Mianserin Impurity 66 (CAS CATO-C4X-136966, C9H12ClNHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Mianserin Impurity 66 (C9H12ClNHCl) is characterized by a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H12ClN HCl |
| Molecular Weight | 206.11 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Mianserin Standards
- Mianserin impurity 02 (CAS 1074-11-9)
- Mianserin Impurity 91 (CAS 1192015-20-5)
- (±)-Mianserin-d3 Hydrochloride (methyl-d3) (CAS 1219804-97-3)
- Mianserin Impurity 80 (CAS 1260761-23-6)
- Mianserin Impurity 114 (CAS 1314960-88-7)
- Mianserin Impurity 102 HCl (CAS 131962-87-3)
- Mianserin impurity 43 (CAS 13665-04-8)
- Mianserin EP impurity B (CAS 140636-22-2)
Recommended Standards
- Trimetazidine EP Impurity H (CAS 53531-01-4)
- Tiamulin impurity 11 (CAS CATO-C4X-221011)
- Resmetirom impurity 74 (CAS 116688-45-0)
- 5-Bromo-4-(2,5-dimethylphenyl)pyrimidine (CAS 941294-35-5)
- N-Acetyl-1-O-(phenylmethyl)-α-muramic Acid Methyl Ester (CAS 40269-09-8)
- ((6-Methoxynaphthalen-2-yl)methyl)hydrazine (CAS 1016536-64-3)
- N-Cyclooctyl-1-[2-methyl-6-(trifluoromethyl)pyrimidin-4-yl]piperidine-4-carboxamide (CAS 1775444-23-9)
- (3-(Aminomethyl)phenyl)(methyl)(methylimino)-lambda6-sulfanone (CAS 2092444-11-4)
- 2,3-diaminopyridine-4-carbonitrile (CAS 1556332-55-8)
- D-[Val]10-Semaglutide (CAS CATO-CPTD788630)
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