Tryptophan Impurity 50 HCl CAS CATO-C4X-137350
| CAS No. | CATO-C4X-137350 |
| Molecular Formula | C18H20N4O6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Tryptophan Impurity 50 HCl is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Tryptophan Impurity 50 HCl (CAS CATO-C4X-137350), a pharmacopoeial impurity reference standard (molecular formula C18H20N4O6HCl, MW 424.84 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Tryptophan Impurity 50 HCl (C18H20N4O6HCl) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 424.84 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Tryptophan Impurity 50 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20N4O6 HCl |
| Molecular Weight | 424.84 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Tryptophan Standards
- Tryptophan Impurity 44 (CAS 101948-12-3)
- L-Tryptophan tert-Butyl Ester HCl (CAS 115692-31-4)
- D-Tryptophan-2′,4′,5′,6′,7′-d5 (indole-d5) (CAS 1202359-57-6)
- Tryptophan Metabolite (HIAA-d5) (CAS 1219802-93-3)
- DL-Tryptophan-d8 (CAS 1233395-85-1)
- Tryptophan Impurity 7 (CAS 13081-15-7)
- Tryptophan EP Impurity A (CAS 132685-02-0)
- Tryptophan EP Impurity A 2HCl (CAS 132685-02-0（free base）)
Recommended Standards
- Varenicline Impurity 71 (CAS CATO-C4X-196271)
- Niraparib Impurity 39 (CAS CATO-C4X-232939)
- Cefazolin EP Impurity D(Cefazolin USP RC J) (CAS 32510-61-5)
- 2-Methyl-1H-imidazo[4,5-b]pyridine-6-carbaldehyde (CAS 1367992-56-0)
- (1S)-7-Methoxy-1,2,3,4-tetrahydronaphthalen-1-ol (CAS 182965-69-1)
- 4-Vinyl-4H-1,2,4-triazole (CAS 125419-53-6)
- Dinoprostone EP Impurity B (CAS 27415-25-4)
- 5-({[(4-Nitrobenzoyl)oxy]imino}methyl)-1,3-benzodioxole (CAS 306732-20-7)
- N-Methyl-1-(7-methyl-1H-benzo[d]imidazol-2-yl)methanamine (CAS 193534-35-9)
- Fibrinogen-Binding Peptide (CAS 137235-80-4)
Why CATO?
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