Daptomycin Impurity 28 CAS CATO-C4X-137828
| CAS No. | CATO-C4X-137828 |
| Molecular Formula | C74H106N16O27 |
| Molecular Weight | 1651.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Daptomycin Impurity 28 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Daptomycin Impurity 28 (CAS CATO-C4X-137828), a pharmacopoeial impurity reference standard (molecular formula C74H106N16O27, MW 1651.72 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Daptomycin Impurity 28 (C74H106N16O27) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 30.0, corresponding to approximately 30 ring(s) or double-bond equivalent(s). With a molecular weight of 1651.72 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Daptomycin Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C74H106N16O27 |
| Molecular Weight | 1651.72 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 30.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 16 |
Related Daptomycin Standards
- Daptomycin Impurity 60 (CAS CATO-C4X-137860)
- Daptomycin Impurity 15 (CAS CATO-C4X-137815)
- Daptomycin Impurity 17 (CAS CATO-C4X-137817)
- Daptomycin Impurity 29 (CAS CATO-C4X-137829)
- Daptomycin Impurity 3 (CAS 883991-21-7)
- Daptomycin Impurity 31 (CAS CATO-C4X-137831)
- Daptomycin Impurity 46 (CAS CATO-C4X-137846)
- Daptomycin Impurity 47 (CAS CATO-C4X-137847)
Recommended Standards
- Peptide WE-14 (CAS 115136-18-0)
- (Asn670,Sta671,Val672)-Amyloid β/A4 Protein Precursor770 (662-675) ammonium salt (CAS 350228-37-4)
- N-Nitroso Daptomycin (CAS CATO-C4X-137854)
- Fondaparinux Sodium Impurity 6 (CAS CATO-C4X-20526)
- Selumetinib Impurity 1 (CAS CATO-C4X-30531)
- Crisaborole impurity 130 (CAS CATO-C4X-2021130)
- Safinamide Impurity 58 (CAS CATO-C4X-159058)
- 4-Styrenesulfonate sodium salt hydrate (CAS 123333-94-8)
- tert-Butyl (2-bromo-5-chloro-4-methylphenyl)carbamate (CAS 1564685-57-9)
- 3-(4-Nitrophenyl)-4,5-dihydro-1,2,4-oxadiazol-5-one (CAS 19932-97-9)
- 1-(2,3-dihydrobenzofuran-7-yl)ethanone (CAS 170730-06-0)
- (R)-2-(3,4-DIchlorophenyl)thiazolidine-4-carboxylic acid (CAS 103261-10-5)
- N-(2-(N-(2,2-Dimethoxyethyl)sulfamoyl)ethyl)-4-methoxybenzamide (CAS 899739-52-7)
- Tirzepatide Impurity 22 X TFA Salt (CAS CATO-C4X-324022)
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