Pioglitazone impurity 53 CAS CATO-C4X-138353
| CAS No. | CATO-C4X-138353 |
| Molecular Formula | C19H22N2O3S |
| Molecular Weight | 358.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Pioglitazone impurity 53.
CATO supplies Pioglitazone impurity 53 (CAS CATO-C4X-138353), a pharmacopoeial impurity reference standard (molecular formula C19H22N2O3S, MW 358.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Pioglitazone impurity 53 (C19H22N2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Pioglitazone impurity 53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H22N2O3S |
| Molecular Weight | 358.45 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Pioglitazone Standards
- Pioglitazone impurity 58 (CAS CATO-C4X-138358)
- Pioglitazone-d4 (major) (CAS 1134163-31-7)
- Pioglitazone impurity 31 (CAS CATO-C4X-138331)
- Pioglitazone (CAS 111025-46-8)
- Pioglitazone-d4 (CAS 1134163-29-3)
- Pioglitazone impurity 61 (CAS CATO-C4X-138361)
- Pioglitazone Impurity 21 (CAS 105355-26-8)
- Pioglitazone impurity 25 (CAS CATO-C4X-138325)
Recommended Standards
- Diltiazem Impurity 24 (CAS CATO-C4X-136824)
- Diltiazem Impurity 11 (CAS 81353-09-5)
- Imipenem Impurity 131 (CAS CATO-C4X-1662131)
- Febuxostat Impurity 47 (CAS 1346238-10-5)
- Erlotinib Impurity 95 (CAS 183320-04-9)
- Bicalutamide Impurity 36 (CAS CATO-C4X-101336)
- Tirofiban Impurity 21 (CAS CATO-C4X-125421)
- 2-Amino-2-methylbutanamide (CAS 59209-90-4)
- 5-Bromo-2-ethoxy-3-methylbenzaldehyde (CAS 708984-81-0)
- Bis(triethyl-lambda5-phosphanyl)bis(((trifluoromethyl)sulfonyl)oxy)platinum (CAS 165336-82-3)
- Palmitoyl hexapeptide-6 (CAS 891498-01-4)
- 4-Bromo-5-(difluoromethyl)-2-methoxynicotinic acid (CAS 1805430-36-7)
- Dopamine Impurity 114 (CAS CATO-C4X-1908114)
- Insulin Lispro (CAS 133107-64-9)
Why CATO?
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