Diltiazem Impurity 11 CAS 81353-09-5

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.81353-09-5
Molecular FormulaC19H22N2O3S
Molecular Weight358.45 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Diltiazem Impurity 11 CAS 81353-09-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Diltiazem Impurity 11.

CATO supplies Diltiazem Impurity 11 (CAS 81353-09-5), a pharmacopoeial impurity reference standard (molecular formula C19H22N2O3S, MW 358.45 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Diltiazem Impurity 11 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 358.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Diltiazem Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC19H22N2O3S
Molecular Weight358.45 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1980
Nitrogen Atoms2
Sulfur Atoms1

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