Rivastigmine N-Oxide Impurity TFA CAS CATO-C4X-138418
| CAS No. | CATO-C4X-138418 |
| Molecular Formula | C14H22N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Rivastigmine N-Oxide Impurity TFA.
As a process- or degradation-related impurity, Rivastigmine N-Oxide Impurity TFA (CAS CATO-C4X-138418, C14H22N2O3C2HF3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Rivastigmine N-Oxide Impurity TFA (C14H22N2O3C2HF3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 380.36 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Rivastigmine N-Oxide Impurity TFA meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H22N2O3 C2HF3O2 |
| Molecular Weight | 380.36 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Rivastigmine Standards
- Rivastigmine Impurity 10 (CAS 105601-04-5)
- rac-Rivastigmine (CAS 105601-20-5)
- Rivastigmine RC 5 (CAS 1070660-34-2)
- Rivastigmine Benzyl Impurity (CAS 1111083-50-1)
- Rivastigmine-d3 (CAS 1133229-21-6)
- Rivastigmine-d5 (CAS 1133229-22-7)
- Rivastigmine Impurity 26 (CAS 1213234-40-2)
- Rivastigmine EP Impurity B (CAS 1230021-28-9)
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- Methylprednisolone impurity 84 (CAS CATO-C4X-191984)
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- Osteoblast Activating Peptide (mouse, rat) (H-7262.0500) (CAS 1222950-80-2)
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