Raltitrexed Impurity 52 CAS CATO-C4X-138652
| CAS No. | CATO-C4X-138652 |
| Molecular Formula | C16H14N2O4 |
| Molecular Weight | 298.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Raltitrexed Impurity 52 (CAS CATO-C4X-138652, C16H14N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H14N2O4, Raltitrexed Impurity 52 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 298.29 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Raltitrexed Impurity 52 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H14N2O4 |
| Molecular Weight | 298.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Raltitrexed Standards
- Raltitrexed Impurity 37 (CAS CATO-C4X-138637)
- Raltitrexed Impurity 43 (CAS CATO-C4X-138643)
- Raltitrexed Impurity 49 (CAS CATO-C4X-138649)
- Raltitrexed Impurity 20 (CAS CATO-C4X-138620)
- Raltitrexed Impurity 13 (CAS CATO-C4X-138613)
- Raltitrexed Impurity 14 (CAS CATO-C4X-138614)
- Raltitrexed Impurity 34 (CAS CATO-C4X-138634)
- Raltitrexed Impurity 39 (CAS CATO-C4X-138639)
Recommended Standards
- Rtitrexed Impurity 26 (CAS CATO-C4X-138626)
- Rimegepant Impurity 29 (CAS CATO-C4X-248729)
- Salbutamol Impurity 96 (CAS 63416-80-8)
- Finerenone Impurity 105 (CAS CATO-C4X-2880105)
- S-Piperacillin Impurity J (CAS CATO-C4X-173273)
- Trimetazidine Impurity 24 (CAS 92432-50-3)
- Doxapram Impurity 29 (CAS CATO-C4X-197329)
- N4-(2-aminoethyl)-N2,N2-dimethylpyrimidine-2,4-diamine (CAS 1342612-71-8)
- 6-Chloro-7-cyclopropyl-7H-purine (CAS 1708288-66-7)
- 1-(2-(Dimethylamino)ethyl)-4-(3-fluoro-4-methylbenzoyl)-3-hydroxy-5-(3-nitrophenyl)-1H-pyrrol-2(5H)-one (CAS 618075-75-5)
- 4-Methylbenzyl benzenesulfonate (CAS 95302-54-8)
- Cefcapene Impurity 11 (CAS CATO-C4X-182411)
- (S)-1-Boc-2-(Hydroxymethyl)piperidine (CAS 134441-93-3)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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