Nifedipine Impurity 12 CAS CATO-C4X-141012
| CAS No. | CATO-C4X-141012 |
| Molecular Formula | C19H18N4O6 |
| Molecular Weight | 398.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Nifedipine Impurity 12 (CAS CATO-C4X-141012, C19H18N4O6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C19H18N4O6, Nifedipine Impurity 12 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 398.37 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C19H18N4O6 |
| Molecular Weight | 398.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Nifedipine Standards
- Nifedipine Pyrimidine Impurity (CAS 80742-11-6)
- Nifedipine Impurity 14 (CAS 108139-78-2)
- Nifedipine impound 37 (CAS CATO-C4X-141037)
- Nifedipine Impurity 17 (CAS CATO-C4X-141017)
- Nifedipine Impurity 32 (CAS CATO-C4X-141032)
- Nifedipine Impurity 5 (CAS 21829-26-5)
- Nifedipine Impurity 30 (CAS CATO-C4X-141030)
- Nifedipine Impurity 6 (CAS 53055-15-5)
Recommended Standards
- Cefpirome Impurity 12 (CAS CATO-C4X-120712)
- Benidipine Impurity 25 (CAS CATO-C4X-112025)
- Bicalutamide Impurity 32 (CAS CATO-C4X-101332)
- Bicalutamide EP Impurity J (CAS 90356-78-8)
- Sacubitril impurity 44 (CAS CATO-C4X-280944)
- Phenylephrine Related Compound G (CAS 1094089-46-9)
- Goserelin BP Impurity 4 Acetate (CAS CATO-C4X-192034)
- 128076-31-3 10-Methyl-1H-pyrrolo[2,1-c][1,4]benzodiazepine-3,5,11(2H,10H,11aH)-trione MFCD22374903 (CAS 128076-31-3)
- (3-(Difluoromethoxy)-5-hydroxyphenyl)(pyridin-4-yl)methanone (CAS 1261787-51-2)
- 2-amino-N-(4-bromo-3-methylphenyl)acetamide hydrochloride (CAS 1235440-42-2)
- 4-(propan-2-yl)furan-2-carbaldehyde (CAS 16015-07-9)
- 1-(2,6-Dichlorophenyl)cyclopropanemethanamine (CAS 1039952-66-3)
- Estrone Impurity 8 (CAS CATO-C4X-21058)
- Semaglutide impurity 86 (CAS CATO-C4X-152686)
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