Estrone Impurity 8 CAS CATO-C4X-21058
| CAS No. | CATO-C4X-21058 |
| Molecular Formula | C31H34O2 |
| Molecular Weight | 438.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 438.60 g/mol gives Estrone Impurity 8 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Estrone Impurity 8 (CAS CATO-C4X-21058, C31H34O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Estrone Impurity 8 (C31H34O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Estrone Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C31H34O2 |
| Molecular Weight | 438.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Estrone Standards
- Estrone beta-D-Glucuronide (CAS 2479-90-5)
- Estrone 3-Sulfate-d5 Sodium Salt (CAS CATO-C4X-21053)
- Estrone 3-Valerate (CAS 128788-26-1)
- Estrone Enol Diacetate (CAS 20592-42-1)
- Estrone 3-Sulfate (CAS 481-97-0)
- Estrone 3-O-Sulfamate (CAS 148672-09-7)
- Estrone Impurity 11 (CAS CATO-C4X-210511)
- Estrone Impurity 12 (CAS CATO-C4X-210512)
Recommended Standards
- Estradiol Impurity 35 (CAS 1373116-15-4)
- (E)-N-Mesityl-4-(5-(4-methylbenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)butanamide (CAS 6605-21-6)
- Cortistatin J (CAS 944804-62-0)
- 2-((5-(Azepan-1-ylsulfonyl)pyridin-2-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)propanamide (CAS 941184-59-4)
- Baloxavir Marboxil Impurity 222 (CAS CATO-C4X-2108222)
- Resmetirom Impurity 10 (CAS CATO-C4X-291210)
- Lusutrombopag Impurity 81 (CAS CATO-C4X-208481)
- 2-(2-Methoxyphenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxylic acid (CAS 1429903-98-9)
- (1-(2-Cyanophenyl)-1H-pyrazol-4-yl)boronic acid (CAS 2225169-32-2)
- Ruxolitinib Impurity 85 (CAS CATO-C4X-205885)
- 4-Bromo-3-(hydroxymethyl)benzonitrile (CAS 905710-66-9)
- Nemonoxacin Impurity 39 (CAS 221221-39-2)
- 2-Methyl-1-benzothiophene-3-carbaldehyde (CAS 30446-99-2)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
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