Domperidone Impurity 28 CAS CATO-C4X-142028
| CAS No. | CATO-C4X-142028 |
| Molecular Formula | C14H20ClN3O2 |
| Molecular Weight | 297.78 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 297.78 g/mol gives Domperidone Impurity 28 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Domperidone Impurity 28 (CAS CATO-C4X-142028) is a certified pharmaceutical impurity reference standard with the molecular formula C14H20ClN3O2 and a molecular weight of 297.78 g/mol.
Structurally, Domperidone Impurity 28 (C14H20ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 297.78 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Domperidone Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H20ClN3O2 |
| Molecular Weight | 297.78 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Domperidone Standards
- Domperidone Impurity 12 (CAS 107618-26-8)
- Domperidone Impurity 8 (CAS 53786-45-1)
- Domperidone Impurity 11 (CAS 85443-52-3)
- Domperidone Impurity 16 (CAS 39677-10-6)
- Domperidone Impurity 15 (CAS 142799-22-2)
- Domperidone Impurity 30 (CAS CATO-C4X-142030)
- Domperidone Impurity 29 (CAS CATO-C4X-142029)
- Domperidone EP Impurity B (CAS 1346598-11-5)
Recommended Standards
- Ivabradine Impurity 27 (CAS 85175-65-1)
- Atazanavir Impurity 14 (CAS 102123-74-0)
- 2-chloro-N-(2-ethoxyacetyl)-N-(2-ethyl-6-methylphenyl)acetamide (CAS CATO-C3D-262297)
- 6-Chloro-N-(2-morpholin-4-ylethyl)-1,3-benzothiazol-2-amine (CAS 1105189-23-8)
- Droperidol EP Impurity A (CAS 2147-83-3)
- Indacaterol Impurity 45 (CAS CATO-C4X-150045)
- Cabergoline Impurity 11 (CAS CATO-C4X-277411)
- tert-Butyl 3-carbamothioylpiperidine-1-carboxylate (CAS 274682-80-3)
- 4-(3-Chlorothiophen-2-yl)pyrimidin-2-amine (CAS 855308-67-7)
- N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-O-benzyl-L-homoserine (CAS 1185841-92-2)
- 903159-15-9 4-(1H-Imidazol-1-ylcarbonyl)-2-methyl-3,4-dihydro-2H-1,4-benzoxazine MFCD15732177 (CAS 903159-15-9)
- 4-Cyclopropoxy-6-(methylthio)nicotinonitrile (CAS 1243320-20-8)
- Ixazomib Impurity 69 (CAS 121-48-2)
- Semaglutide impurity 109 (CAS CATO-C4X-2226109)
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