Amiodarone Impurity 26 CAS CATO-C4X-142526
| CAS No. | CATO-C4X-142526 |
| Molecular Formula | C20H20O3 |
| Molecular Weight | 308.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Amiodarone Impurity 26 is closely related to a steroid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Amiodarone Impurity 26 (CAS CATO-C4X-142526, C20H20O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Amiodarone Impurity 26 (C20H20O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Amiodarone Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H20O3 |
| Molecular Weight | 308.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Amiodarone Standards
- Amiodarone Impurity 13 (CAS 83790-87-8)
- Amiodarone Impurity 24 (CAS CATO-C4X-142524)
- Amiodarone Impurity 25 (CAS CATO-C4X-142525)
- Amiodarone Impurity 27 (CAS CATO-C4X-142527)
- Amiodarone EP Impurity E (CAS 52490-15-0)
- Amiodarone Impurity 50 (CAS CATO-C4X-142550)
- Amiodarone Impurity 49 (CAS CATO-C4X-142549)
- Amiodarone Impurity 38 (CAS 138320-26-0)
Recommended Standards
- Acetylcysteine impurity 74 (CAS CATO-C4X-153274)
- Lisinopril EP Impurity H (CAS 138247-43-5)
- Mianserin Impurity 113 (CAS CATO-C4X-1369113)
- Bestatin (CAS 58970-76-6)
- Dapagliflozin Impurity 47 (CAS CATO-C4X-113847)
- Doxapram Impurity 35 (CAS CATO-C4X-197335)
- Rosuvastatin Impurity 250 (CAS CATO-C4X-1169250)
- 3-(2-Methoxyphenyl)-N,N-dimethylprop-2-yn-1-amine (CAS 222614-15-5)
- N,N-Dimethyl-4′-nitro[1,1′-biphenyl]-4-amine (CAS 2143-87-5)
- 3-Amino-N-(2-(diethylamino)ethyl)benzamide, 97% (CAS 104458-37-9)
- N-(2-(Furan-3-yl)ethyl)-4-phenylbutanamide (CAS 1428356-64-2)
- (11aR)-N,N-Dicyclohexyl-10,11,12,13-tetrahydrodiindeno[7,1-de:1',7'-fg][1,3,2]dioxaphosphocin-5-amine (CAS 500997-68-2)
- 1-(2-(3-Methylpyrrolidin-1-yl)ethyl)-1h-pyrazol-3-amine (CAS 1343218-82-5)
- Biotinyl-CBP501 Affinity Peptide trifluoroacetate salt (CAS 2022956-39-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com