Loratadine Impurity 34 CAS CATO-C4X-142634
| CAS No. | CATO-C4X-142634 |
| Molecular Formula | C22H21ClN2O3 |
| Molecular Weight | 396.87 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Loratadine Impurity 34 (CAS CATO-C4X-142634) is a certified pharmaceutical impurity reference standard with the molecular formula C22H21ClN2O3 and a molecular weight of 396.87 g/mol.
Loratadine Impurity 34 (C22H21ClN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Loratadine Impurity 34 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H21ClN2O3 |
| Molecular Weight | 396.87 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Loratadine Standards
- Loratadine Impurity 36 (CAS CATO-C4X-142636)
- Loratadine Epoxide (CAS 1189694-51-6)
- Loratadine impurity 11 (CAS 165739-62-8)
- Loratadine Impurity 35 (CAS CATO-C4X-142635)
- Loratadine Impurity 37 (CAS CATO-C4X-142637)
- Loratadine Impurity 38 (CAS 403484-49-1)
- Loratadine Impurity 89 (CAS CATO-C4X-142689)
- Loratadine EP Impurity A (CAS 133284-74-9)
Recommended Standards
- N-Nitroso N-Desmethyl Azelastine (CAS CATO-C4X-139636)
- Clofazimine Impurity 27 (CAS CATO-C4X-207127)
- Ziprasidone Impurity 68 (CAS CATO-C4X-124068)
- GSK 4112 (CAS 1216744-19-2)
- Sofosbuvir Impurity 80 (CAS CATO-C4X-105280)
- Brivaracetam Impurity 158 (CAS 855209-27-7)
- Niraparib Impurity 32 (CAS CATO-C4X-232932)
- (R)-5-(methylsulfonyl)isoindoline-1-carboxylic acid (CAS 1389390-05-9)
- 4-Methoxy-2-methylbenzenethiol (CAS 698-81-7)
- 6,8-Dibromo-1,2,3,4-tetrahydroquinolin-4-one (CAS 263896-33-9)
- 3-Cyano-4-methylpyridine (CAS 5444-01-9)
- 4-Amino-6-methylthiochroman 1,1-dioxide (CAS 1037148-88-1)
- 5,5-Dimethyl-2,5-dihydro-3,3'-biisoxazole (CAS 502181-53-5)
- Semaglutide impurity 195 (CAS CATO-C4X-2226195)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com