Galanthamine Impurity 42 (4aS,6S,8aR) CAS CATO-C4X-143542

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-143542
Molecular FormulaC24H25NO4
Molecular Weight391.46 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Galanthamine Impurity 42 (4aS,6S,8aR) CAS CATO-C4X-143542 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Galanthamine Impurity 42 (4aS,6S,8aR).

CATO supplies Galanthamine Impurity 42 (4aS,6S,8aR) (CAS CATO-C4X-143542), a pharmacopoeial impurity reference standard (molecular formula C24H25NO4, MW 391.46 g/mol) used for the identification and quantification of trace impurities in APIs.

Galanthamine Impurity 42 (4aS,6S,8aR) (C24H25NO4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

As a certified reference material (CRM), Galanthamine Impurity 42 (4aS,6S,8aR) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC24H25NO4
Molecular Weight391.46 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms1

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