Gadoteridol Impurity 12 TriHCl CAS CATO-C4X-225712
| CAS No. | CATO-C4X-225712 |
| Molecular Formula | C8H17N3O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Gadoteridol Impurity 12 TriHCl is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Gadoteridol Impurity 12 TriHCl (CAS CATO-C4X-225712, C8H17N3O2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Gadoteridol Impurity 12 TriHCl (C8H17N3O2HCl) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Gadoteridol Impurity 12 TriHCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H17N3O2 3*HCl |
| Molecular Weight | 223.70 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Gadoteridol Standards
- Gadoteridol Impurity 14 HCl (CAS 114873-37-9(free))
- Gadoteridol (CAS 120066-54-8)
- Gadoteridol impurity 40 (CAS 137145-75-6)
- Gadoteridol Impurity 3 (CAS 138884-13-6)
- Gadoteridol Impurity 5 (CAS 148407-91-4)
- Gadoteridol Impurity 13 (CAS 192329-72-9)
- Gadoteridol impurity 29 (CAS 213312-49-3)
- Gadoteridol Impurity 6 (CAS 214195-92-3)
Recommended Standards
- Gadobutrol Impurity 143 4HCl (CAS CATO-C4X-2120143)
- Doxofylline impurity 45 (CAS 96474-41-8)
- Bedaquiline (1S,2R) Isomer Impurity 1 (CAS 857086-93-2)
- 3-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]propan-1-amine hydrochloride (CAS 1461708-25-7)
- 1-((Chloromethyl)sulfonyl)-2-ethylpyrrolidine (CAS 1341214-52-5)
- (3R,4S)-1-Methyl-4-phenyl-3-piperidinemethanol (CAS 176022-02-9)
- 2-((4-Acetamidophenyl)thio)acetic acid (CAS 3406-74-4)
- 5-Bromo-2-chlorobenzyl Chloride (CAS 928758-19-4)
- 6-(Trifluoromethyl)pyridazine-3-carbonitrile (CAS 1206524-27-7)
- Hexapeptide-10 (CAS 146439-94-3)
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