Naphazoline Impurity 10 CAS CATO-C4X-144010
| CAS No. | CATO-C4X-144010 |
| Molecular Formula | C14H17N3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
As a process- or degradation-related impurity, Naphazoline Impurity 10 (CAS CATO-C4X-144010, C14H17N3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Naphazoline Impurity 10 (C14H17N3HCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C14H17N3 2*HCl |
| Molecular Weight | 263.77 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Naphazoline Standards
- Naphazoline Impurity 2 (CAS 1019-21-2)
- Naphazoline EP Impurity C (CAS 132-75-2)
- Naphazoline Impurity 1 (CAS 17518-47-7)
- Naphazoline EP Impurity D (CAS 22126-67-6)
- Naphazoline EP Impurity A (CAS 36321-43-4)
- Naphazoline Impurity 6 (CAS 36660-46-5)
- Naphazoline Nitrate (CAS 5144-52-5)
- Naphazoline hydrochloride (CAS 550-99-2)
Recommended Standards
- Midecamycin Impurity 13 (CAS CATO-C4X-312213)
- Topiramate Impurity 17 (CAS 97240-80-7)
- Upadacitinib Impurity 76 (CAS 2270173-67-4)
- Reproterol impurity 1 (CAS CATO-C4X-30991)
- n-Ethyl-2,5-dimethylbenzenesulfonamide (CAS 19925-28-1)
- 1-(4-tert-Butylbenzoyl)-2-methylpiperazine (CAS 1240578-12-4)
- 5-Methylimidazo[1,2-a]pyrimidin-7(8H)-one (CAS 55662-34-5)
- [1,1'-Biphenyl]-2-yl(cyclohexyl)methanone (CAS 963-92-8)
- 8-Chloro-5-methoxyquinolin-4-ol (CAS 63010-43-5)
- Des-Ala35-Tirzepatide (CAS CATO-CPTD788939)
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