Flurbiprofen Impurity 134 CAS CATO-C4X-1444134
| CAS No. | CATO-C4X-1444134 |
| Molecular Formula | C30H35FO2 |
| Molecular Weight | 446.60 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Flurbiprofen Impurity 134 (CAS CATO-C4X-1444134, C30H35FO2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Flurbiprofen Impurity 134 (C30H35FO2) contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Flurbiprofen Impurity 134 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H35FO2 |
| Molecular Weight | 446.60 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Flurbiprofen Standards
- Flurbiprofen Impurity 143 (CAS CATO-C4X-1444143)
- Flurbiprofen Impurity 64 (CAS CATO-C4X-144464)
- Flurbiprofen Impurity 125 (CAS CATO-C4X-1444125)
- Flurbiprofen Impurity 131 (CAS CATO-C4X-1444131)
- Flurbiprofen Impurity 132 (CAS CATO-C4X-1444132)
- Flurbiprofen Impurity 95 (CAS CATO-C4X-144495)
- Flurbiprofen Impurity 62 (CAS CATO-C4X-144462)
- Flurbiprofen Impurity 98 (CAS CATO-C4X-144498)
Recommended Standards
- Clindamycin Impurity 86 (CAS CATO-C4X-134186)
- Clindamycin Impurity 142 (CAS CATO-C4X-1341142)
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- Clindamycin Impurity 141 (CAS CATO-C4X-1341141)
- Dutasteride EP Impurity G (CAS 1430804-85-5)
- Benzenesulfonic Impurity 2 (CAS 1352414-88-0)
- Vaborbactam Impurity 5 (CAS CATO-C4X-34775)
- (E)-tert-Butyl 3-((dimethylamino)methylene)-4-oxopyrrolidine-1-carboxylate (CAS 1819364-04-9)
- N-(4-phenoxyphenyl)-2-(4-phenylpiperazin-1-yl)acetamide (CAS 692773-82-3)
- 7-Chloro-1-(2,4-dichlorophenyl)heptan-1-one (CAS 898786-16-8)
- 1-(6-(Trifluoromethyl)pyridin-2-yl)cyclopropan-1-amine dihydrochloride (CAS 1384265-58-0)
- Succinyl-CoA (CAS 604-98-8)
- 2-(Phenylamino)pyridine-3-sulfonamide (CAS 1340791-40-3)
- Semaglutide Impurity 183 (CAS 159541-28-3)
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