Flurbiprofen Impurity 131 CAS CATO-C4X-1444131
| CAS No. | CATO-C4X-1444131 |
| Molecular Formula | C28H35FO4 |
| Molecular Weight | 454.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Flurbiprofen Impurity 131 (CAS CATO-C4X-1444131) is a certified pharmaceutical impurity reference standard with the molecular formula C28H35FO4 and a molecular weight of 454.57 g/mol.
Structurally, Flurbiprofen Impurity 131 (C28H35FO4) contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 454.57 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Flurbiprofen Impurity 131 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C28H35FO4 |
| Molecular Weight | 454.57 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Flurbiprofen Standards
- Flurbiprofen Impurity 125 (CAS CATO-C4X-1444125)
- Flurbiprofen Impurity 132 (CAS CATO-C4X-1444132)
- Flurbiprofen Impurity 95 (CAS CATO-C4X-144495)
- Flurbiprofen Impurity 134 (CAS CATO-C4X-1444134)
- Flurbiprofen Impurity 143 (CAS CATO-C4X-1444143)
- Flurbiprofen Impurity 64 (CAS CATO-C4X-144464)
- Flurbiprofen Impurity 62 (CAS CATO-C4X-144462)
- Flurbiprofen Impurity 98 (CAS CATO-C4X-144498)
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