Flurbiprofen Impurity 85 CAS CATO-C4X-144485
| CAS No. | CATO-C4X-144485 |
| Molecular Formula | C11H15NO3 |
| Molecular Weight | 209.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Flurbiprofen Impurity 85 (CAS CATO-C4X-144485, C11H15NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Flurbiprofen Impurity 85 (C11H15NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H15NO3 |
| Molecular Weight | 209.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Flurbiprofen Standards
- Flurbiprofen Impurity 44 (CAS CATO-C4X-144444)
- Flurbiprofen Impurity 61 (CAS 95037-98-2)
- Flurbiprofen Impurity 90 (CAS 145983-05-7)
- Flurbiprofen Impurity 79 (CAS CATO-C4X-144479)
- Flurbiprofen Impurity 162 (CAS 861795-19-9)
- Flurbiprofen Impurity 57 (CAS 81937-32-8)
- Flurbiprofen EP Impurity D (CAS 42771-79-9)
- Flurbiprofen EP Impurity E (CAS 137045-30-8)
Recommended Standards
- Nimodipine impurity 24 (CAS CATO-C4X-138524)
- Phenylephrine Impurity 89 (CAS CATO-C4X-146789)
- Oxybuprocaine EP Impurity B (CAS 23442-22-0)
- Norepinephrine Impurity 36 (CAS 121-28-8)
- Afatinib Impurity 22 (CAS 162012-67-1)
- Quetiapine EP Impurity A 1/2 Fumarate (CAS 844639-07-2（free base）)
- Roxithromycin Impurity 15 (CAS 89268-03-1)
- 4-(3,5-Dimethoxyphenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazole-3-thiol (CAS 517869-97-5)
- 6-(4-Chloropyridin-3-yl)-6-oxohexanenitrile (CAS 890100-88-6)
- 1,2-O-Cyclohexylidene-3-O-methyl-α-D-glucofuranose (CAS 13322-87-7)
- NLX-101 (CAS 635323-95-4)
- 2-Mercapto-3-(4-methylcyclohexyl)quinazolin-4(3H)-one (CAS 690683-99-9)
- Androstenediol-3-acetate-17-benzoate (CAS 5953-63-9)
- Insulin Degludec Impurity 20 (CAS CATO-C4X-215720)
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