Tizanidine Impurity 48 CAS CATO-C4X-144548
| CAS No. | CATO-C4X-144548 |
| Molecular Formula | C6H5ClN2O2 |
| Molecular Weight | 172.57 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tizanidine Impurity 48.
As a process- or degradation-related impurity, Tizanidine Impurity 48 (CAS CATO-C4X-144548, C6H5ClN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Tizanidine Impurity 48 (C6H5ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Tizanidine Impurity 48 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H5ClN2O2 |
| Molecular Weight | 172.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tizanidine Standards
- Tizanidine Impurity 50 (CAS CATO-C4X-144550)
- Tizanidine Impurity 46 (CAS CATO-C4X-144546)
- Tizanidine impurity 34 (CAS CATO-C4X-144534)
- Tizanidine EP Impurity E (CAS 30536-19-7)
- Tizanidine Unknown Impurity (CAS 5391-53-7)
- Tizanidine Impurity 53 (CAS CATO-C4X-144553)
- Tizanidine Impurity 52 (CAS CATO-C4X-144552)
- Tizanidine Impurity 44 (CAS 13907-88-5)
Recommended Standards
- N-(4-Amino-6-chloropyrimidin-5-yl)formamide (CAS 7501-32-8)
- 5-Chlorosalicylic Acid (CAS 321-14-2)
- Methyl 6-Chloropyrimidine-4-carboxylate (CAS 6627-22-1)
- 2,4-Dihyroxy-3-Chlorobenzenaldehyde (CAS 131088-00-1)
- Pimavanserin Impurity 17 (CAS CATO-C4X-193817)
- Rosuvastatin Impurity 93 (CAS CATO-C4X-116993)
- Eldecalcitol Impurity 64 (CAS CATO-C4X-214064)
- 2-(Prop-1-en-2-yl)thiophene (CAS 30616-73-0)
- 2-bromo-3-(methylsulfanyl)thiophene (CAS 94781-39-2)
- 2-(6-(Benzyloxy)hexyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2030409-63-1)
- 3-(4-(Ethoxycarbonyl)-1,3,5-trimethyl-1H-pyrrol-2-yl)propanoic acid (CAS 1283390-40-8)
- N-(3,4-Dimethylphenyl)-2-((4-ethyl-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 557065-37-9)
- 3,4-Dimethanesulfonylbenzonitrile (CAS 1208406-84-1)
- Neuropeptide Y (18-36) (CAS 114495-97-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com