Tizanidine EP Impurity E CAS 30536-19-7
| CAS No. | 30536-19-7 |
| Molecular Formula | C6H4ClN3S |
| Molecular Weight | 185.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Tizanidine EP Impurity E (CAS 30536-19-7), a pharmacopoeial impurity reference standard (molecular formula C6H4ClN3S, MW 185.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Tizanidine EP Impurity E (C6H4ClN3S) contains a nitrile group, sulfur-containing functionality, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H4ClN3S |
| Molecular Weight | 185.63 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Tizanidine Standards
- Tizanidine impurity 34 (CAS CATO-C4X-144534)
- Tizanidine Unknown Impurity (CAS 5391-53-7)
- Tizanidine Impurity 44 (CAS 13907-88-5)
- Tizanidine Impurity 46 (CAS CATO-C4X-144546)
- Tizanidine impurity 35 (CAS 32863-29-9)
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- Tizanidine Impurity 55 (CAS CATO-C4X-144555)
- Tizanidine Impurity 50 (CAS CATO-C4X-144550)
Recommended Standards
- Capivasertib Impurity 45 (CAS CATO-C4X-331245)
- Famotidine impurity 63 (CAS CATO-C4X-139263)
- 3-Butoxy-2-chloropyridine (CAS 1003711-47-4)
- Famotidine Impurity 54 (CAS CATO-C4X-139254)
- Safinamide Impurity 2 (CAS 1160513-60-9)
- Malic Acid Impurity 7 (CAS CATO-C4X-25097)
- Quetiapine EP Impurity F HCl (CAS CATO-C4X-124445)
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- 2-amino-4,5,6,7-tetrahydro-1,3-benzothiazole-4-carboxylic acid hydrochloride (CAS 1808580-34-8)
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- (5Z)-5-[(4-Methoxyphenyl)methylidene]-3-methyl-1,3-thiazolidine-2,4-dione (CAS 642474-13-3)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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