Norfloxacin Impurity 36 CAS CATO-C4X-146836
| CAS No. | CATO-C4X-146836 |
| Molecular Formula | C12H10Cl2FNO3 |
| Molecular Weight | 306.12 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 306.12 g/mol gives Norfloxacin Impurity 36 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Norfloxacin Impurity 36 (CAS CATO-C4X-146836) is a certified pharmaceutical impurity reference standard with the molecular formula C12H10Cl2FNO3 and a molecular weight of 306.12 g/mol.
Based on its molecular formula C12H10Cl2FNO3, Norfloxacin Impurity 36 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 306.12 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Norfloxacin Impurity 36 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H10Cl2FNO3 |
| Molecular Weight | 306.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Norfloxacin Standards
- Norfloxacin Impurity 34 (CAS CATO-C4X-146834)
- Norfloxacin Impurity 35 (CAS CATO-C4X-146835)
- Norfloxacin Impurity K (CAS 70459-07-3)
- Norfloxacin Impurity 48 (CAS CATO-C4X-146848)
- Norfloxacin Impurity C171 (CAS 106847-39-6)
- Norfloxacin Impurity 61 (CAS CATO-C4X-146861)
- Norfloxacin Impurity 63 (CAS 106847-42-1)
- Norfloxacin (CAS 70458-96-7)
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- 1-Benzyl-5-bromo-6-fluorobenzotriazole (CAS 1365272-70-3)
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- 4-Acetamido-3-methyltetrahydrofuran-3-carboxylic acid (CAS 1532828-67-3)
- N-(5-(tert-pentyl)-1,3,4-thiadiazol-2-yl)pyrazine-2-carboxamide (CAS 522598-25-0)
- 2,3-Difluoroacetophenone (CAS 18355-80-1)
- 1-Pentanone, 5-methoxy-1-[4-(trifluoromethyl) phenyl] -, oxime (CAS 61747-22-6)
- 2,2,2-Trichloroethanol (CAS 115-20-8)
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