Indometacin Impurity 46 CAS CATO-C4X-147046
| CAS No. | CATO-C4X-147046 |
| Molecular Formula | C12H12N2O4 |
| Molecular Weight | 248.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Indometacin Impurity 46 (C12H12N2O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 248.23 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Indometacin Impurity 46 (CAS CATO-C4X-147046), a pharmacopoeial impurity reference standard (molecular formula C12H12N2O4, MW 248.23 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Indometacin Impurity 46 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H12N2O4 |
| Molecular Weight | 248.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Indometacin Standards
- Indometacin Impurity 36 (CAS CATO-C4X-147036)
- Indometacin EP Impurity C (CAS 4018-82-0)
- Indometacin Impurity 20 (CAS 73301-01-6)
- Indometacin Impurity 27 (CAS CATO-C4X-147027)
- Indometacin Impurity 16 (CAS CATO-C4X-147016)
- Indometacin Impurity 48 (CAS CATO-C4X-147048)
- Indometacin Impurity 49 (CAS CATO-C4X-147049)
- Indometacin Impurity 52 (CAS CATO-C4X-147052)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com