Naltrexone impurity 53 CAS CATO-C4X-147553
| CAS No. | CATO-C4X-147553 |
| Molecular Formula | C21H26N2O5 |
| Molecular Weight | 386.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Naltrexone impurity 53 (C21H26N2O5) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Naltrexone impurity 53 (CAS CATO-C4X-147553), a pharmacopoeial impurity reference standard (molecular formula C21H26N2O5, MW 386.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Naltrexone impurity 53 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H26N2O5 |
| Molecular Weight | 386.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Naltrexone Standards
- Naltrexone Impurity 21 (CAS 64643-76-1)
- Naltrexone Impurity 15 (CAS 111129-14-7)
- Naltrexone EP Impurity E (CAS 767615-69-0)
- Naltrexone impurity 30 (CAS 112242-13-4)
- Naltrexone Impurity 62 (CAS CATO-C4X-147562)
- Naltrexone Impurity 67 (CAS CATO-C4X-147567)
- Naltrexone impurity 45 (CAS CATO-C4X-147545)
- Naltrexone impurity 33 (CAS CATO-C4X-147533)
Recommended Standards
- Avanafil Impurity 88 (CAS 2250243-52-6)
- Ketorolac Impurity 71 (CAS CATO-C4X-166971)
- Avanafil Impurity 19 (CAS 2250242-12-5)
- Olodaterol impurity 23 (CAS CATO-C4X-194323)
- Carteolol Impurity 30 (CAS CATO-C4X-228730)
- Olmesartan Impurity 52 (CAS 1040405-56-8)
- Lidocaine EP Impurity F(Hydrochloride) (CAS 857170-72-0)
- 2-(3-Chloro-5-fluoro-4-methoxyphenyl)acetonitrile (CAS 1000540-93-1)
- Methyl 4-bromoindoline-6-carboxylate (CAS 2067333-71-3)
- Methomyl D3 (CAS 1398109-07-3)
- Levofloxacin Impurity 31 (CAS CATO-C4X-137131)
- 4-(4-(Difluoromethoxy)phenoxy)-3-(trifluoromethyl)aniline (CAS 87294-32-4)
- tert-Butyl (1-(3-chlorophenyl)-3-oxopropyl)carbamate (CAS 277745-53-6)
- Palmitoyl Hexapeptide-12 (CAS 171263-26-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com