Avanafil Impurity 19 CAS 2250242-12-5
| CAS No. | 2250242-12-5 |
| Molecular Formula | C20H26N4O4 |
| Molecular Weight | 386.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Avanafil Impurity 19 (CAS 2250242-12-5, C20H26N4O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C20H26N4O4, Avanafil Impurity 19 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 386.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H26N4O4 |
| Molecular Weight | 386.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 4 |
Related Avanafil Standards
- Avanafil Impurity 88 (CAS 2250243-52-6)
- Avanafil Impurity 79 (CAS 330785-82-5)
- Avanafil Impurity 5 (CAS 372117-54-9)
- Avanafil Impurity 89 (CAS 2250243-36-6)
- Avanafil Impurity 125 (CAS CATO-C4X-1118125)
- Avanafil Impurity 27 (CAS 330785-84-7)
- Avanafil Impurity 40 (CAS 1638497-25-2)
- Avanafil Impurity 52 (CAS CATO-C4X-111852)
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