Ceftaroline Fosamil Impurity 24 CAS CATO-C4X-148324
| CAS No. | CATO-C4X-148324 |
| Molecular Formula | C22H21N8O8PS4 |
| Molecular Weight | 684.68 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Ceftaroline Fosamil Impurity 24 (CAS CATO-C4X-148324, C22H21N8O8PS4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, an amide group, a sulfone group, a phosphate ester group, a hydroxyl group, an ether linkage, Ceftaroline Fosamil Impurity 24 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 684.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H21N8O8PS4 |
| Molecular Weight | 684.68 g/mol |
| Purity | ≥90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 16.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 8 |
| Sulfur Atoms | 4 |
Related Ceftaroline Standards
- Ceftaroline Fosamil Impurity 7 (CAS 229016-73-3)
- Ceftaroline Fosamil Impurity 19 (CAS 953037-68-8)
- Ceftaroline Fosamil Impurity 20 (CAS CATO-C4X-148320)
- Ceftaroline Impurity 4 (CAS CATO-C4X-14834)
- Ceftaroline Impurity 12 (CAS 400827-68-1)
- Ceftaroline Impurity 15 (CAS CATO-C4X-148315)
- Ceftaroline Impurity 6 (CAS 1286218-72-1)
- Ceftaroline Impurity 16 (CAS CATO-C4X-148316)
Recommended Standards
- N-[4-(Trifluoromethoxy)phenyl]-2-{[4-({4-[({[4-(trifluoromethoxy)phenyl]carbamoyl}methyl)sulfanyl]phenyl}sulfanyl)phenyl]sulfanyl}acetamide (CAS 882079-20-1)
- Yadanzioside A (CAS 95258-15-4)
- N,N′-1,2-Phenylenebis[2-(diphenylphosphino)benzamide] (CAS 659727-33-0)
- Cefamandole Impurity 25 (CAS CATO-C4X-122125)
- Peramivir Impurity 46 (CAS CATO-C4X-183346)
- Lenvatinib Impurity 37 (CAS CATO-C4X-114037)
- Pimavanserin impurity 54 (CAS 4734-09-2)
- 2'-Methyl-6'-(trifluoromethyl)-3',4'-dihydro-2'H-spiro[piperidine-4,1'-pyrrolo[1,2-a]pyrazine] hydrochloride (CAS 1956334-55-6)
- Ethyl 2-(4,6-dimethyl-2-oxo-3-(o-tolylsulfonyl)pyridin-1(2H)-yl)acetate (CAS 321431-61-2)
- 2-(Pyridin-4-yl)tetrahydrofuran-3-amine dihydrochloride (CAS 1955520-83-8)
- 7-Chloroquinolin-4-ol hydrochloride (CAS 71799-41-2)
- Ethyl 2-(aminomethyl)cyclohexane-1-carboxylate (CAS 1466910-45-1)
- Z-Leu-Glu(OMe)-Thr-DL-Asp(OMe)-fluoromethylketone (N-1975.0001) (CAS 1926163-60-1)
- D-[Thr]7-Liraglutide (CAS CATO-C4X-199237)
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