Ceftaroline Impurity 4 CAS CATO-C4X-14834

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-14834
Molecular FormulaC22H21N8O8PS4
Molecular Weight684.68 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ceftaroline Impurity 4 CAS CATO-C4X-14834 chemical structure

Description

The molecular framework of Ceftaroline Impurity 4 (C22H21N8O8PS4) is characterized by a flavonoid core, an amide group, a sulfone group, a phosphate ester group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

CATO supplies Ceftaroline Impurity 4 (CAS CATO-C4X-14834), a pharmacopoeial impurity reference standard (molecular formula C22H21N8O8PS4, MW 684.68 g/mol) used for the identification and quantification of trace impurities in APIs.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Ceftaroline Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC22H21N8O8PS4
Molecular Weight684.68 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)16.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms8
Sulfur Atoms4

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