Loxoprofen Impurity 52 CAS CATO-C4X-148852
| CAS No. | CATO-C4X-148852 |
| Molecular Formula | C18H22O5 |
| Molecular Weight | 318.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Loxoprofen Impurity 52 (CAS CATO-C4X-148852) is a certified pharmaceutical impurity reference standard with the molecular formula C18H22O5 and a molecular weight of 318.36 g/mol.
The molecular framework of Loxoprofen Impurity 52 (C18H22O5) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H22O5 |
| Molecular Weight | 318.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Loxoprofen Standards
- Loxoprofen Impurity 108 (CAS CATO-C4X-1488108)
- Loxoprofen impurity 123 (CAS CATO-C4X-1488123)
- Loxoprofen Impurity 130 (CAS 261521-19-1)
- Loxoprofen Impurity 145 (CAS 2274853-20-0)
- Loxoprofen Impurity 30 (CAS 308279-38-1)
- Loxoprofen Impurity 35 (CAS CATO-C4X-148835)
- Loxoprofen Impurity 81 (CAS CATO-C4X-148881)
- Loxoprofen Impurity 137 (CAS CATO-C4X-1488137)
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- 1-Cyclopropyl-1H-1,2,3-triazole-5-carboxylic acid (CAS 1784650-04-9)
- 4-{2-[(2-Fluorobenzyl)oxy]ethyl}piperidinehydrochloride (CAS 1219980-76-3)
- (R)-3-Amino-5-(1-aminoethyl)benzonitrile (CAS 2789706-25-6)
- 4-[3-(dimethylamino)phenoxy]benzene-1-carboximidamide hydrochloride (CAS 1394041-01-0)
- ethyl 2-methyl-2-(triazol-2-yl)propanoate (CAS 2170180-17-1)
- 3-(4-Chlorophenyl)-5-oxopyrrolidine-2-carboxylic acid (CAS 1026093-70-8)
- Insulin Degludec Impurity 25 (CAS CATO-C4X-215725)
Why CATO?
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