Itraconazole Impurity 86 CAS CATO-C4X-149786
| CAS No. | CATO-C4X-149786 |
| Molecular Formula | C35H38Cl2N8O4 |
| Molecular Weight | 705.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Itraconazole Impurity 86 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Itraconazole Impurity 86 (CAS CATO-C4X-149786) is a certified pharmaceutical impurity reference standard with the molecular formula C35H38Cl2N8O4 and a molecular weight of 705.63 g/mol.
Structurally, Itraconazole Impurity 86 (C35H38Cl2N8O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 20.0, corresponding to approximately 20 ring(s) or double-bond equivalent(s). With a molecular weight of 705.63 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Itraconazole Impurity 86 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C35H38Cl2N8O4 |
| Molecular Weight | 705.63 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Itraconazole Standards
- Itraconazole Impurity 24 (CAS CATO-C4X-149724)
- Itraconazole EP Impurity F (CAS 89848-51-1)
- Itraconazole Impurity 90 (Mixture of Diastereomers) (CAS CATO-C4X-149790)
- Itraconazole (CAS 84625-61-6)
- Itraconazole-d3 (CAS 1217512-35-0)
- Itraconazole-d5(major) (CAS 1217510-38-7)
- Itraconazole-D9 (CAS 1309272-50-1)
- Itraconazole-d9 (CAS CATO-C4X-149751)
Recommended Standards
- 1-(Butan-2-yl)-4-{4-[4-(4-{[2-(2,4-dichlorophenyl)-2-[(1h-1,2,4-triazol-1-yl)methyl]-1,3-dioxolan-4-yl]methoxy}phenyl)piperazin-1-yl]phenyl}-4,5-dihydro-1h-1,2,4-triazol-5-one (CAS 2049588-24-9)
- Blood Group A Tetrasaccharide (CAS 59957-92-5)
- (2R,4S)-Itraconazole (Mixture of Diastereomers) (CAS 873066-43-4)
- RMC6236 Intermediate 6 (CAS 3034241-56-7)
- Azacitidine Impurity 76 (CAS CATO-C4X-138876)
- Lemborexant impurity 13 (CAS CATO-C4X-304213)
- Bosentan Impurity 23 (CAS CATO-C4X-156423)
- Di-tert-butyl 1,4-dioxo-3,6-di(thiophen-2-yl)pyrrolo[3,4-c]pyrrole-2,5(1H,4H)-dicarboxylate (CAS 1046864-83-8)
- 2-(3-Cyanocyclopentyl)acetic acid (CAS 1369100-63-9)
- 3-(5-Chlorothiophen-2-yl)-5,6-dihydro-4H-pyrrolo[3,2-d]isoxazole (CAS 603068-05-9)
- Methyl 4-Chloro-6-methoxyquinazoline-8-carboxylate (CAS 1240480-28-7)
- 7-Amino-2-methyl-4H-chromen-4-one (CAS 30779-70-5)
- YYJ34Z13SH 611-34-7 5-Aminoquinoline 5-Quinolinamine (9CI) Quinoline, 5-amino- 5-22-10-00297 (Beilstein Handbook Reference) BRN 0114479 CCRIS 1680 EINECS 210-266-1 NSC 27982 5-Quinolinamine 5-Quinolylamine UNII-YYJ34Z13SH (CAS 611-34-7)
- Des-Pro-Pro-Tirzepatide (CAS CATO-CPTD788696)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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