Cefmetazole Impurity 65 CAS CATO-C4X-150765
| CAS No. | CATO-C4X-150765 |
| Molecular Formula | C16H20N6O5S3 |
| Molecular Weight | 472.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cefmetazole Impurity 65.
As a process- or degradation-related impurity, Cefmetazole Impurity 65 (CAS CATO-C4X-150765, C16H20N6O5S3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Cefmetazole Impurity 65 (C16H20N6O5S3) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H20N6O5S3 |
| Molecular Weight | 472.56 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 3 |
Related Cefmetazole Standards
- Cefmetazole Impurity 2 (CAS CATO-C4X-15072)
- Cefmetazole Impurity 22 (CAS CATO-C4X-150722)
- Cefmetazole Impurity 27 (CAS CATO-C4X-150727)
- Cefmetazole Impurity 28 (CAS CATO-C4X-150728)
- Cefmetazole Impurity 33 (CAS CATO-C4X-150733)
- Cefmetazole Impurity 38 (CAS CATO-C4X-150738)
- Cefmetazole Impurity 5 (CAS CATO-C4X-15075)
- Cefmetazole Impurity 62 (CAS CATO-C4X-150762)
Recommended Standards
- Lubiprostone Impurity 21 (CAS CATO-C4X-113621)
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- Triisopropyl((5-(methylthio)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-2-yl)oxy)silane (CAS 2621937-59-3)
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- Carvedilol EP Impurity A (CAS 1198090-73-1)
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- 3-Boc-aminomethyl-1,2,3,4-tetrahydro-isoquinoline (CAS 885273-85-8)
- 4-{imidazo[1,2-a]pyridin-2-ylmethoxy}benzaldehyde (CAS 118001-76-6)
- 1-(4-Methoxyphenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride (CAS 306934-94-1)
- 1-(3-Phenylprop-2-yn-1-yl)piperidine (CAS 2568-57-2)
- Loratadine Impurity B (CAS 38093-12-8)
- 2-(tert-Butoxy)-4-cyclopropoxy-3-(trifluoromethyl)pyridine (CAS 1243286-23-8)
- Semaglutide Impurity 142 (CAS CATO-C4X-2226142)
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