Norepinephrine impurity 88 HCl CAS CATO-C4X-151488
| CAS No. | CATO-C4X-151488 |
| Molecular Formula | 2*C16H15NO6 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Norepinephrine impurity 88 HCl is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Norepinephrine impurity 88 HCl (CAS CATO-C4X-151488), a pharmacopoeial impurity reference standard (molecular formula C16H15NO6HCl, MW 353.75 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Norepinephrine impurity 88 HCl is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 353.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Norepinephrine impurity 88 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | 2*C16H15NO6 HCl |
| Molecular Weight | 353.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Norepinephrine Standards
- Norepinephrine Impurity 50 (CAS 100622-09-1)
- Norepinephrine Impurity 103 (CAS 102743-86-2)
- Norepinephrine EP Impurity F (CAS 103-49-1)
- Norepinephrine Impurity 107 (CAS 112346-92-6)
- Norepinephrine Impurity 28 (CAS 117883-03-1)
- Norepinephrine Impurity 22 (CAS 1197-09-7)
- Norepinephrine Impurity 36 (CAS 121-28-8)
- Norepinephrine Impurity 161 (CAS 1215-29-8（free acid）)
Recommended Standards
- Ticagrelor Impurity 125 (CAS CATO-C4X-1093125)
- Rifampicin Impurity 14 (CAS CATO-C4X-145614)
- Tacrolimus Impurity 52 (CAS CATO-C4X-130052)
- Fmoc-Cys((R)-2,3-di(palmitoyloxy)-propyl)-OH (CAS 139573-77-6)
- 1-[4-(1,5-dimethyl-1h-pyrazol-4-yl)-6-(trifluoromethyl)pyrimidin-2-yl]piperidine-3-carboxylic acid (CAS 1006348-78-2)
- 2,2',5-Trichlorobiphenyl (CAS 37680-65-2)
- 1-(3-Methoxypropyl)-1H-pyrazol-4-ol (CAS 1600091-35-7)
- N-(4-iodophenyl)-3-oxobutanamide (CAS 38418-25-6)
- 2-(chloromethyl)-5-(3-chlorophenyl)-1,3-oxazole (CAS 64640-15-9)
- Peptide Fmoc-Thi-Thi-OH (CAS CATO-CPTD788552)
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