Rebamipide Impurity 46 CAS CATO-C4X-152346
| CAS No. | CATO-C4X-152346 |
| Molecular Formula | C23H21ClN2O6 |
| Molecular Weight | 456.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Rebamipide Impurity 46.
Rebamipide Impurity 46 (CAS CATO-C4X-152346) is a certified pharmaceutical impurity reference standard with the molecular formula C23H21ClN2O6 and a molecular weight of 456.88 g/mol.
Rebamipide Impurity 46 (C23H21ClN2O6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Rebamipide Impurity 46 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H21ClN2O6 |
| Molecular Weight | 456.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Rebamipide Standards
- Rebamipide impurity 26 (CAS CATO-C4X-152326)
- Rebamipide Impurity 37 (CAS 1984832-97-4)
- Rebamipide Impurity 10 (CAS CATO-C4X-152310)
- Rebamipide Impurity 63 (CAS CATO-C4X-152363)
- Rebamipide Impurity 64 (CAS CATO-C4X-152364)
- Rebamipide Impurity 43 (CAS 1028268-32-7)
- Rebamipide Impurity 41 (CAS CATO-C4X-152341)
- Rebamipide Impurity 45 (CAS CATO-C4X-152345)
Recommended Standards
- NAV 2729 (CAS 419547-11-8)
- N-Nitroso Flucloxacillin Impurity 21 (CAS CATO-C4X-164721)
- 1,4-Diamino-7-chloro-2-(4-phenoxyphenoxy)anthracene-9,10-dione (CAS 88605-39-4)
- (3-(2-Chlorophenyl)-5-methylisoxazol-4-yl)(8-(6-fluoropyridin-2-yl)-1-oxa-4,8-diazaspiro[4.5]Decan-4-yl)methanone (CAS 303151-57-7)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
- Cefpirome Impurity 39 (CAS CATO-C4X-120739)
- Sitafloxacin Isomer Impurity 7(SSS) (CAS CATO-C4X-11557)
- Aroclor 1232 (CAS 11141-16-5)
- N-(2,4-dimethoxyphenyl)-2-((3-methyl-4-oxo-7-(p-tolyl)-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040631-78-4)
- Gadoteridol Impurity 14 HCl (CAS 114873-37-9(free))
- (3-Amino-4-chlorophenyl)(2-methylmorpholino)methanone (CAS 926268-57-7)
- 4-Propyl-3-(pyridin-2-yl)-1h-pyrazol-5-amine (CAS 1229025-40-4)
- n1-Cyclopropyl-6-methylbenzene-1,2-diamine (CAS 1353945-54-6)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
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