(3-(2-Chlorophenyl)-5-methylisoxazol-4-yl)(8-(6-fluoropyridin-2-yl)-1-oxa-4,8-diazaspiro[4.5]Decan-4-yl)methanone CAS 303151-57-7
| CAS No. | 303151-57-7 |
| Molecular Formula | C23H22ClFN4O3 |
| Molecular Weight | 456.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3-(2-Chlorophenyl)-5-methylisoxazol-4-yl)(8-(6-fluoropyridin-2-yl)-1-oxa-4,8-diazaspiro[4.5]Decan-4-yl)methanone is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(3-(2-Chlorophenyl)-5-methylisoxazol-4-yl)(8-(6-fluoropyridin-2-yl)-1-oxa-4,8-diazaspiro[4.5]Decan-4-yl)methanone (CAS 303151-57-7) is a high-purity analytical reference standard with the molecular formula C23H22ClFN4O3 and a molecular weight of 456.90 g/mol.
Based on its molecular formula C23H22ClFN4O3, (3-(2-Chlorophenyl)-5-methylisoxazol-4-yl)(8-(6-fluoropyridin-2-yl)-1-oxa-4,8-diazaspiro[4.5]Decan-4-yl)methanone contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 456.90 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H22ClFN4O3 |
| Molecular Weight | 456.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chlorophenyl Standards
- 4-{[(4-chlorophenyl)methyl]sulfanyl}-5-methoxy-2-({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)pyrimidine (CAS 478042-71-6)
- Methyl 2-(2-(4-chlorophenyl)acetamido)-4-methyl-5-(m-tolylcarbamoyl)thiophene-3-carboxylate (CAS 335409-04-6)
- 1-Butyl-3-((4-chlorophenyl)sulfonyl)-2-imino-10-methyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606962-56-5)
- N-(3-(4-Chlorophenyl)-1-(4-phenylthiazol-2-yl)-1H-pyrazol-5-yl)benzamide (CAS 74101-29-4)
- 6-(((4-Chlorophenyl)thio)methyl)-2-((3,4-dichlorobenzyl)thio)-N-methylpyrimidin-4-amine (CAS 478261-62-0)
- 4-(4-(3-Chlorophenyl)-4-(pyrrolidine-1-carbonyl)piperidin-1-yl)-1-(4-fluorophenyl)butan-1-one (CAS 2924-46-1)
- 1-[(4-Chlorophenyl)sulfanyl]-4-{[(2,6-dichlorophenyl)sulfanyl]methyl}-2-nitrobenzene (CAS 477869-65-1)
- 5-(4-Chlorophenyl)-N-(2,4-dichlorophenyl)-1-(p-tolyl)-1H-pyrazole-3-carboxamide (CAS 477713-25-0)
Recommended Standards
- N-Nitroso Flucloxacillin Impurity 21 (CAS CATO-C4X-164721)
- (4,5-Dibromo-6-oxo-1,6-dihydropyridazin-1-yl)methyl 3,4-dichlorobenzoate (CAS 439108-06-2)
- Rebamipide Impurity 46 (CAS CATO-C4X-152346)
- 2-(4-Ethoxyphenyl)-4-oxo-4H-chromen-3-yl 4-chlorobenzenesulfonate (CAS 298215-03-9)
- 1-fluoro-3-(2-methoxyethenyl)benzene (CAS 188400-90-0)
- 5-Amino-2,3-dihydro-3-oxo-1H-pyrazole-4-carboxylic acid (CAS 412301-20-3)
- N-(2-{[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]amino}ethyl)urea (CAS 303153-08-4)
- N-(4-Methyl-2-nitrophenyl)furan-2-carboxamide (CAS 79324-93-9)
- 1-(3,5-dimethylbenzoyl)piperidin-3-amine (CAS 1305859-79-3)
- PU-WS13 (CAS 1454619-14-7)
- Tetramethylammonium fluoride trihydrate (CAS 111203-44-2)
- 2-(3-Methoxy-5-methyl-4-nitro-1H-pyrazol-1-yl)ethan-1-amine (CAS 1006440-49-8)
- Methyl 4-(4-chlorophenyl)pyrrolidine-3-carboxylate (CAS 939758-07-3)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
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