Thioctic acid Impurity 83 CAS CATO-C4X-152683
| CAS No. | CATO-C4X-152683 |
| Molecular Formula | C12H23ClO3 |
| Molecular Weight | 250.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Thioctic acid Impurity 83 (CAS CATO-C4X-152683) is a certified pharmaceutical impurity reference standard with the molecular formula C12H23ClO3 and a molecular weight of 250.76 g/mol.
The molecular framework of Thioctic acid Impurity 83 (C12H23ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
As a certified reference material (CRM), Thioctic acid Impurity 83 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H23ClO3 |
| Molecular Weight | 250.76 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| Halogen Content | Cl-containing |
Related Thioctic Standards
- Thioctic acid Impurity 37 (CAS CATO-C4X-152637)
- Thioctic acid Impurity 41 (CAS CATO-C4X-152641)
- Thioctic acid Impurity 87 (CAS CATO-C4X-152687)
- Thioctic acid Impurity 25 (CAS 728854-75-9)
- Thioctic Acid EP Impurity A (CAS 1204245-29-3)
- Thioctic acid impurity 72 (CAS CATO-C4X-152672)
- Thioctic acid impurity 61 (CAS 26825-92-3)
- Thioctic acid Impurity 40 (CAS 91009-31-3)
Recommended Standards
- 2-(4-Chlorophenyl)ethyl cyclohexyl ketone (CAS 898788-61-9)
- 1,1,2,2,3,3-Hexachloropropane (CAS 15600-01-8)
- 2-(3-Chlorophenyl)ethyl cyclohexyl ketone (CAS 898787-56-9)
- 3-(Phenylsulfanyl)propane-1-sulfonyl chloride (CAS 85577-60-2)
- Dyclonine Impurity 19 (CAS CATO-C4X-188119)
- Creatine Impurity 1 (CAS 98924-69-7)
- Omeprazole Impurity 43 (CAS 151602-50-5)
- Acetylcysteine EP Impurity D (CAS 18725-37-6)
- Tigecycline (CAS 220620-09-7)
- 4-Methyl-5-(2-(methylthio)ethyl)-1H-imidazol-2(3H)-one (CAS 885296-28-6)
- 2-(3,4-Difluorophenyl)ethanamine (CAS 220362-31-2)
- (2,4-Difluoropyridin-3-yl)methanamine (CAS 1824158-80-6)
- (4-Chlorobicyclo[2.2.2]Octan-1-yl)methanol (CAS 94994-17-9)
- Semaglutide impurity 203 (CAS CATO-C4X-2226203)
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