Amorolfine Impurity 46 CAS CATO-C4X-154246
| CAS No. | CATO-C4X-154246 |
| Molecular Formula | C21H35NO |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Amorolfine Impurity 46 (CAS CATO-C4X-154246, C21H35NOHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C21H35NOHCl, Amorolfine Impurity 46 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 353.98 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Amorolfine Impurity 46 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H35NO HCl |
| Molecular Weight | 353.98 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Amorolfine Standards
- Amorolfine EP Impurity F (CAS 106614-66-8)
- Amorolfine Hydrochloride - Impurity G (CAS 1260498-34-7)
- Amorolfine EP Impurity G HCl (CAS 1260498-35-8)
- Amorolfine EP Impurity B (CAS 142347-84-0)
- Amorolfine Impurity 87 (CAS 1688675-10-6)
- Amorolfine Impurity 89 (CAS 1689944-83-9)
- Amorolfine Impurity 62 (CAS 1800302-57-1)
- trans-Amorolfine (CAS 2134097-34-8)
Recommended Standards
- Canagliflozin Impurity 24 (CAS 2348-31-4)
- Emedastine EP Impurity A (CAS 101953-61-1)
- Diquafosol Impurity 29 (CAS 22256-98-0（free base）)
- 2-(3,5-Dichlorophenyl)-7,7,9-trimethyl-2-azaspiro[4.5]decane-1,3-dione (CAS 286009-45-8)
- Methyl 5-(3,4-dichlorophenyl)-1-phenyl-1H-pyrazole-3-carboxylate (CAS 318256-21-2)
- 1-(3-Hydroxypropyl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one (CAS 923283-93-6)
- 1-(3-Chloroprop-1-yn-1-yl)-4-phenethoxybenzene (CAS 1184146-34-6)
- 3-(Bromomethyl)-1-cyclopropyl-1H-pyrazole (CAS 2201840-09-5)
- 1-Benzyl-3-(4-chlorophenyl)urea (CAS 13208-51-0)
- Semaglutide impurity 236 (CAS CATO-C4X-2226236)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com