Atenolol EP Impurity J HCI CAS CATO-C4X-154923
| CAS No. | CATO-C4X-154923 |
| Molecular Formula | C11H16N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 260.72 g/mol gives Atenolol EP Impurity J HCI distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Atenolol EP Impurity J HCI (CAS CATO-C4X-154923, C11H16N2O3HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Atenolol EP Impurity J HCI (C11H16N2O3HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Atenolol EP Impurity J HCI under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H16N2O3 HCl |
| Molecular Weight | 260.72 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Atenolol Standards
Recommended Standards
- Zolpidem Impurity 1 (CAS 109461-64-5)
- Piperazine Impurity 15 (CAS 10430-90-7)
- Solifenacin Succinate EP Impurity F (CAS 774517-20-3)
- 3-(5-Bromo-2-methoxyphenyl)-2,2-dimethylpropanoic acid (CAS 1274124-39-8)
- ethyl 2-(5-bromo-4-formyl-2-methoxyphenoxy)acetate (CAS 428477-60-5)
- (2R,3R,4S,5S)-4-(Aminomethyl)-5-(hydroxymethyl)-2-(6-((3-iodobenzyl)amino)-9H-purin-9-yl)tetrahydrofuran-3-ol (CAS 522607-99-4)
- Methyl 2-methoxy-5-(morpholinomethyl)nicotinate (CAS 924300-49-2)
- 4-(2-(Piperidin-1-yl)ethoxy)aniline hydrochloride (CAS 774462-55-4)
- 2-Mercapto-3-(2-(trifluoromethyl)phenyl)-3,5,6,7,8,9-hexahydro-4h-cyclohepta[4,5]thieno[2,3-d]pyrimidin-4-one (CAS 565195-77-9)
- Insulin Degludec Impurity 11 (CAS CATO-C4X-215711)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com