Bosentan Impurity 12 CAS CATO-C4X-156412
| CAS No. | CATO-C4X-156412 |
| Molecular Formula | C30H43N5O6S |
| Molecular Weight | 601.76 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bosentan Impurity 12.
As a process- or degradation-related impurity, Bosentan Impurity 12 (CAS CATO-C4X-156412, C30H43N5O6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Bosentan Impurity 12 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 601.76 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Bosentan Impurity 12 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H43N5O6S |
| Molecular Weight | 601.76 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Bosentan Standards
Recommended Standards
- Revefenacin-d3 (CAS 909800-36-8(unlabeled))
- N-[4-[2-[[2-[4-[bis(methylsulfonyl)amino]phenoxy]-1,1,2,2-tetradeuterioethyl]-methylamino]ethyl]phenyl]-N-methylsulfonylmethanesulfonamide (CAS 1397192-78-7)
- Forestine (CAS 91794-14-8)
- Oxybutynin Impurity 9 (CAS CATO-C4X-19729)
- Tofacitinib Impurity 135 (CAS CATO-C4X-1079135)
- Cisatracurium besylate EP Impurity A (CAS 1075727-04-6(free base))
- Tirzepatide Impurity 57 (CAS CATO-C4X-324057)
- Pentanoic acid, 5-[[(2R)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-1-oxo-3-[(triphenylmethyl)thio]propyl]amino]- (CAS 1100364-96-2)
- [Bis[3,5-bis(trifluoromethyl)phenyl][3,6-dimethoxy-2′,4′,6′-tris(1-methylethyl)[1,1′-biphenyl]-2-yl]phosphine-κP]chlorogold (CAS 1334547-76-0)
- 6-Bromo-2,3-dihydro-1H-inden-4-ol (CAS 1782804-85-6)
- 1-Chloro-3-fluoro-5-nitro-2-propoxybenzene (CAS 1881321-96-5)
- N-(4-(Methylsulfonyl)phenyl)thiophene-2-sulfonamide (CAS 900135-66-2)
- Integrin Binding Peptide trifluoroacetate salt (CAS 278792-07-7)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
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