Choline impurity 4 CAS CATO-C4X-15874
| CAS No. | CATO-C4X-15874 |
| Molecular Formula | C8H19N2O2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Choline impurity 4 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Choline impurity 4 (CAS CATO-C4X-15874) is a certified pharmaceutical impurity reference standard with the molecular formula C8H19N2O2Cl and a molecular weight of 210.70 g/mol.
The molecular framework of Choline impurity 4 (C8H19N2O2Cl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C8H19N2O2 Cl |
| Molecular Weight | 210.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 0.0 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Choline Standards
- 2,4-D Choline salt (CAS 1048373-72-3)
- Choline chloride-1-<SUP>13</SUP>C (CAS 1219388-71-2)
- Choline (47-50% in Water) (CAS 123-41-1)
- Choline Fenofibrate Impurity 13 (CAS 134612-84-3)
- Choline fenofibrate Impurity 23 (CAS 154356-97-5)
- Choline Impurity 5 (CAS 162440-04-2)
- CHOLINE IODIDE (CAS 17773-10-3)
- Choline Fenofibrate Impurity 26 (CAS 1797121-54-0)
Recommended Standards
- Ambroxol Impurity 91 (CAS CATO-C4X-108591)
- Metoclopramide impurity 54 (CAS CATO-C4X-141554)
- Thioctic Acid Impurity 11 (CAS 1071-71-2)
- Benzyl 4-(3-pyrrolidinyloxy)benzoate hydrochloride (CAS 1220034-69-4)
- 5-Chloro-3-nitroimidazo[1,2-a]pyridine (CAS 67625-23-4)
- 2-Bromomethyl-5-chloro-1,3-dinitrobenzene (CAS 1000341-01-4)
- (o-Nitrophenyl)pyruvic Acid 2-Oxime (CAS 27878-36-0)
- tert-Butyl 2-(1-(4-(methoxycarbonyl)phenyl)ethylidene)hydrazine-1-carboxylate (CAS 349111-15-5)
- Bilastine Impurity 20 (CAS 202189-76-2)
- Cholecystokinin, CCK Tetrapeptide (30-33) (CAS 35144-91-3)
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