Thioctic Acid Impurity 11 CAS 1071-71-2
| CAS No. | 1071-71-2 |
| Molecular Formula | C8H13ClO3 |
| Molecular Weight | 192.64 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 192.64 g/mol gives Thioctic Acid Impurity 11 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Thioctic Acid Impurity 11 (CAS 1071-71-2) is a certified pharmaceutical impurity reference standard with the molecular formula C8H13ClO3 and a molecular weight of 192.64 g/mol.
The molecular framework of Thioctic Acid Impurity 11 (C8H13ClO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Thioctic Acid Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H13ClO3 |
| Molecular Weight | 192.64 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
Related Thioctic Standards
- Thioctic Acid Impurity 51 (CAS 56535-97-8)
- Thioctic acid Impurity 42 (CAS 90435-60-2)
- Thioctic Acid Impurity 52 (CAS CATO-C4X-152652)
- Thioctic acid impurity 62 (CAS 93892-06-9)
- Thioctic acid Impurity 79 (CAS 105986-59-2)
- Thioctic Acid Impurity 48 (CAS 2975-17-9)
- Thioctic Acid Impurity 50 (CAS CATO-C4X-152650)
- Thioctic acid Impurity 33 (CAS 50628-92-7)
Recommended Standards
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