Dasatinib Impurity 24 CAS CATO-C4X-160724
| CAS No. | CATO-C4X-160724 |
| Molecular Formula | C11H9Cl2N3OS |
| Molecular Weight | 302.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Dasatinib Impurity 24 (CAS CATO-C4X-160724, C11H9Cl2N3OS) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Dasatinib Impurity 24 (C11H9Cl2N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), Dasatinib Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H9Cl2N3OS |
| Molecular Weight | 302.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Dasatinib Standards
- Dasatinib Impurity 22 (CAS CATO-C4X-160722)
- Dasatinib Impurity 23 (CAS CATO-C4X-160723)
- Dasatinib impurity 61 (CAS CATO-C4X-160761)
- Dasatinib Impurity 19 (CAS CATO-C4X-160719)
- Dasatinib Impurity 20 (CAS CATO-C4X-160720)
- Dasatinib Impurity 21 (CAS CATO-C4X-160721)
- Dasatinib Impurity 73 (CAS CATO-C4X-160773)
- Dasatinib Impurity 54 (CAS 127116-19-2)
Recommended Standards
- Eltenac (CAS 72895-88-6)
- (4-Bromo-2-hydroxyphenyl)(thiomorpholino)methanone (CAS 1249939-74-9)
- N-[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-pyridyl]cyclobutanecarboxamide (CAS 2246899-16-9)
- 2,2,2-trifluoro-1-(oxolan-2-yl)ethyl trifluoromethanesulfonate (CAS 1315366-26-7)
- Esmolol Impurity 49 (CAS CATO-C4X-189149)
- Flibanserin Impurity 5 (CAS CATO-C4X-19815)
- Glipizide Impurity 37 (CAS 350983-37-8)
- (S)-1-(1-Phenyl-1h-pyrazol-4-yl)ethan-1-ol (CAS 1394051-20-7)
- 3,4-Dichloro-1-(5-chloro-2-methoxyphenyl)-1H-pyrrole-2,5-dione (CAS 329224-72-8)
- 1-(4-Propylpyridin-3-yl)butan-1-one (CAS 142505-14-4)
- 3-(5-(1-Methyl-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid (CAS 305376-97-0)
- Besudil Impurity 5 (CAS CATO-C4X-29885)
- 5-(4-Fluorobenzenesulfonyl)pentylamine (CAS 1343982-73-9)
- Semaglutide Impurity 144 (CAS 394210-59-4)
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