Dasatinib Impurity 54 CAS 127116-19-2
| CAS No. | 127116-19-2 |
| Molecular Formula | C11H17ClN4O |
| Molecular Weight | 256.73 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Dasatinib Impurity 54 is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 256.73 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Dasatinib Impurity 54 (CAS 127116-19-2, C11H17ClN4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dasatinib Impurity 54 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H17ClN4O |
| Molecular Weight | 256.73 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Dasatinib Standards
- Dasatinib Impurity 63 (CAS 617-07-2)
- Dasatinib Impurity 18 (CAS CATO-C4X-160718)
- Dasatinib Impurity 41 (CAS 863127-76-8)
- Dasatinib Impurity 52 (CAS 2169776-07-0)
- Dasatinib Impurity 53 (CAS 2169767-97-7)
- Dasatinib Impurity 68 (CAS CATO-C4X-160768)
- Dasatinib Impurity 26 (CAS CATO-C4X-204526)
- Dasatinib Impurity 19 (CAS CATO-C4X-160719)
Recommended Standards
- Metoclopramide Impurity 125 (CAS 476615-04-0)
- N-Nitroso Tulobuterol (CAS CATO-C4X-213417)
- Sertraline Impurity 69 (CAS CATO-C4X-134469)
- Bilastine Impurity 41 (CAS 2761944-43-6)
- Difenidol Impurity 11 (CAS 778-66-5)
- Brimonidine EP Impurity F (CAS 151110-15-5)
- Ibuprofen Impurity 157 (CAS 62049-65-4)
- (S)-Methyl 2-((S)-2-((tert-butoxycarbonyl)amino)-3-methylbutanamido)propanoate (CAS 15275-65-7)
- [5-(propan-2-yl)Thiophen-3-yl]methanamine (CAS 943731-87-1)
- 1,5-Dichloro-2-fluoro-3-nitrobenzene (CAS 501644-37-7)
- tert-Butyl (2-(2-aminoacetamido)cyclohexyl)(ethyl)carbamate (CAS 1353953-03-3)
- 2-(2-Bromo-3,5-dichlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 1256781-65-3)
- 1-(2-(Trifluoromethyl)phenyl)piperidin-4-amine (CAS 1017047-14-1)
- Des-Ala35-Tirzepatide (CAS CATO-CPTD788939)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com