Dasatinib Impurity 27 CAS CATO-C4X-160727

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-160727
Molecular FormulaC16H12Cl3N5OS
Molecular Weight428.72 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Dasatinib Impurity 27 CAS CATO-C4X-160727 chemical structure

Description

CATO manufactures Dasatinib Impurity 27 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Dasatinib Impurity 27 (CAS CATO-C4X-160727) is a certified pharmaceutical impurity reference standard with the molecular formula C16H12Cl3N5OS and a molecular weight of 428.72 g/mol.

Dasatinib Impurity 27 (C16H12Cl3N5OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

Physical & Chemical Properties

Molecular FormulaC16H12Cl3N5OS
Molecular Weight428.72 g/mol
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Halogen ContentCl-containing
Nitrogen Atoms5
Sulfur Atoms1

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