Dasatinib Impurity 3 CAS 910297-51-7
| CAS No. | 910297-51-7 |
| Molecular Formula | C20H22ClN7OS |
| Molecular Weight | 443.95 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Dasatinib Impurity 3 (C20H22ClN7OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Dasatinib Impurity 3 (CAS 910297-51-7) is a certified pharmaceutical impurity reference standard with the molecular formula C20H22ClN7OS and a molecular weight of 443.95 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H22ClN7OS |
| Molecular Weight | 443.95 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Dasatinib Standards
- Dasatinib Impurity 34 (CAS CATO-C4X-160734)
- Dasatinib Impurity 35 (CAS CATO-C4X-160735)
- Dasatinib Impurity 28 (CAS 1184919-23-0)
- Dasatinib Impurity 25 (CAS CATO-C4X-160725)
- Dasatinib Impurity 26 (CAS CATO-C4X-160726)
- Dasatinib Impurity 27 (CAS CATO-C4X-160727)
- Dasatinib Impurity 45 (CAS 1025814-13-4)
- Dasatinib Impurity 59 (CAS CATO-C4X-160759)
Recommended Standards
- 4-{[(4-chlorophenyl)methyl]sulfanyl}-6-(4-methoxyphenyl)-2-phenylpyrimidine-5-carbonitrile (CAS 338395-37-2)
- 1,3,3,3-Tetramethyldisiloxanyl tris(trimethylsilyl) Silicate (CAS 38147-00-1)
- 2-((5-(4-Chlorophenyl)-4-(furan-2-ylmethyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (CAS 771517-41-0)
- 1-{[5-(2-chlorophenyl)-1,2-oxazol-3-yl]methyl}-4-(diphenylmethyl)piperazine (CAS 339019-78-2)
- Promethazine impurity 59 (CAS CATO-C4X-141859)
- Argatroban Impurity 130 (CAS CATO-C4X-1007130)
- Tamsulosin Impurity 53 (CAS CATO-C4X-118753)
- 2-Phenyl-N-(2-((6-phenylpyridazin-3-yl)oxy)ethyl)ethene-1-sulfonamide (CAS 1207062-20-1)
- Ethyl 2-(2-{3-phenyl[(3-chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)benzoate (CAS 303150-08-5)
- 2-(6-fluoro-1H-1,3-benzodiazol-1-yl)acetic acid (CAS 1515850-56-2)
- 5-(2-Methoxyethoxy)-1H-pyrazol-3-amine (CAS 120292-05-9)
- tert-butyl 2,3-dihydro-1,4-oxazine-4-carboxylate (CAS 1221347-27-8)
- 2-Chloroquinolin-6-amine (CAS 238756-47-3)
- Des-Val23-Tirzepatide (CAS CATO-CPTD788950)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com